Researcher: Prof Ayesha A Motala
i) Potter PC, Pelteret R, Reynold L, Motala AA, Kibel MA.
Born before arrival – A study of the New Somerset Hospital, Cape Town.
S Afr Med J 1984; 66 : 377-380.
ii) Omar MAK, Seedat MA, Dyer RB, Rajput MC, Motala AA, Joubert SM.
The prevalence of diabetes mellitus in a large group of South African Indians.
S Afr Med J 1985; 67 : 924-926.
iii) Omar MAK, Seedat MA, Dyer RB, Motala AA.
The 2-hour plasma insulin response to a glucose load in Indians with diabetes mellitus and IGT.
S Afr Med J 1986: 70 : 301.
iv) Omar MAK, Motala AA, Jialal I, Seedat MA.
Microvascular complications in young South African Indians with non-insulin
dependent diabetes mellitus.
Transplantation Proceedings 1986; 1483-1484.
v) Omar MAK, Motala AA, Jialal I, Seedat MA.
Non insulin dependent diabetes mellitus of the young and microvascular complications in South African Indians.
Diabetes Research 1986; 3 : 483-485.
vi) Omar MAK, Cristopher l, Motala AA.
Management of Diabetes Mellitus. Part I.
Goals of therapy and diet.
S Afr Med J 1987; 71 : 580-584.
vii) Motala AA, Omar MAK, Seedat MA.
Impaired Glucose Tolerance.
S Afr Med J 1987; 71 : 612-613.
viii) Omar MAK, Hammond MG, Motala AA, Seedat MA.
HLA class I and II antigens in South African Indians with non-insulin diabetes mellitus.
Diabetes 1988; 37 : 796-799.
ix) Omar MAK, Seedat MA, Dyer RB, Motala AA.
Diabetes and hypertension in South African Indians : A community study.
S Afr Med 1988; 635-637.
x) Omar MAK, Hammond MG, Desai RK, Motala AA, Aboo, Seedat MA.
HLA Class I and II antigens in South African Blacks with Graves’ Disease.
Clin Immun & Immunopath 1990; 54 : 98-102.
xi) Omar MAK, Motala AA.
Insulin-dependent diabetes mellitus : recent development (Editorial).
S Afr Med J 1990; 78 : 178-179.
xii) King H, Rewers M on behalf of the WJO Ad Hoc Diabetes Reporting Group (Ahren B, Motala AA, Omar MAK, Seedat MA, Zukowski W).
Diabetes in adults is now a Third World Problem.
Bulletin of the World Health Organisation, 1991; 69: 643-648.
xiii) Randeree HA, Omar MAK, Motala AA, Seedat MA.
Effect of insulin therapy on blood pressure in NIDDM patients with secondary failure.
Diabetes Care 1992; 15: 1258-1263.
xiv) Motala AA, Omar MAK.
The value of glycosylated haemoglobin as a substitute for the oral glucose tolerance test in the detection of impaired glucose tolerance (IGT).
Diabetes Res Clin Pract 1992; 17: 199-207.
xv) Motala AA, Omar MAK, Gouws E.
High Risk of progression to NIDDM in South African Indians with impaired glucose tolerance.
Diabetes 1993; 42: 556-563.
xvi) Omar MAK, Seedat MA, Motala AA, Dyer RB, Becker P.
The prevalence of diabetes mellitus and impaired glucose tolerance in a group of urban South African Blacks. South Afr Med J 1993; 83 : 641-643.
xvii) Omar MAK, Motala AA, Seedat MA.
Effects of captopril and razocin on renal function in diabetes.
South Afr Med J 1993; 83 : 365.
xviii) King H, Rewers M, WHO Ad Hoc Reporting Group.(Ahren B, Motala AA, Omar MAK, Seedat MA, Zukowski W.
Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults. Diabetes Care 1993; 16: 157-177.
xix) Motala AA, Omar MAK.
Evaluation of WHO and NDDG criteria for impaired glucose tolerance.
Diabetes Res Clin Pract 1994; 23: 103-109.
xx) Motala AA, Omar MAK.
Evidence for impaired pancreatic beta cell function in South African Indians
with Impaired Glucose Tolerance.
Diabetic Med 1994; 11: 437-444.
xxi) Omar MAK, Motala AA, Seedat MA, Knight LT, Dyer RB, Becker PJ.
South African Indians show a high prevalence of NIDDM and bimodality in plasma glucose distribution patterns.
Diabetes Care, 1994; 17: 70-73.
xxii) Davoren PM, Motala AA, Alberti KGMM.
The effect of acipimox on glucose disposal in non-insulin dependent diabetes is dependent on the lowering of non-esterified fatty acid levels.
Diab. Nutr. Metab. 1995; 8: 99-104.
xxiii) Omar MAK, Motala AA, Pirie FJ.
The significance of a positive family history in South African Indians with NIDDM. Diabetes Res. Clin Pract 1996; 34: 513-516.
xxiv) Peters AL, Davidson MB, Schriger DL, Hasselblad V. For the Meta-analysis Research Group on the Diagnosis of Diabetes using glycated hemoglobin levels (Bennett P, Boucher BJ, Motala A, Yudkin JS).
A clinical approach for the diagnosis of diabetes mellitus. An analysis using
glycosylated hemoglobin levels. JAMA 276: 1246-1252, 1996.
xxv) Motala AA, Omar MAK, Gouws E.
Transient impaired glucose tolerance in South African Indians does not carry a risk for progression to NIDDM.
Diabetes Care 1997; 20 : 1101 – 1107.
xxvi) Omar MAK, Motala AA.
Fasting in Ramadaan and the Diabetic patient.
Diabetes Care 1997; 20: 1925-1926.
xxvii) Motala AA.
Microalbuminuria in diabetes mellitus.
South African Medical Journal 1998; 88: 365-366.
xxviii) Motala AA.
Microalbuminuria in diabetes mellitus – management.
South African Medical Journal 1999; 89: 795-797.
xxix) PJ Ojwang, RJ Pegoraro, PA Lanning, L Rom, A Motala, FJ Pirie,
MAK Omar.
Point mutation (C 446 S) in the thyroid hormone receptor gene in a black
South African kindred with thyroid hormone resistance syndrome.
S Afr Med J 1999; 89: 1205-1210.
xxx) Omar MA, Motala AA, Randeree HA.
Does optimal diabetes control using intensive treatment influence by confluence long-term diabetic complications?
S Afr Med J. 1995 Dec ; 85(12) : 1265-1266.
xxxi) Amod A, Motala AA, Pirie FJ, Omar MA.
Diagnosis of Cushing’s syndrome.
S Afr Med J. 1997 Mar;87(3 Suppl):384-386.
xxxii) Pirie FJ, York DF, Motala AA, Omar MAK.
Fluorescent automated single-stranded conformation (F-SSCP) analysis is able to detect a point mutation at the extreme 5 end of a PCR product.
Clinical Biochemistry 1999; 32: 481-484.
xxxiii) Motala AA, Omar MAK, Pirie FJ.
Type 1 diabetes mellitus in Africa: epidemiology and pathogenesis.
Diabetes International 2000; 10(2): 44-47.
xxxiv) Levitt NS, Unwin NC, Bradshaw D, Kitange HM, Mbanya J-CN, Mollentze WF, Omar MAK, Motala AA, Joubert G, Masuki G, Machibya H.
Application of the new ADA criteria for the diagnosis of diabetes to population studies in sub-saharan Africa.
Diabetic Medicine 2000; 17: 381-385.
xxxv) Pirie FJ, Hammond MG, Motala AA, Omar MAK,
HLA class II antigens in South African Blacks with type 1 diabetes.
Tissue Antigens, 2001 Apr; 57 (4): 348-52
xxxvi) Motala AA, Pirie FJ, Gouws E, Amod A, Omar MAK.
Microvascular Complications in South African patients with long duration diabetes.
S Afr Med J. 2001(Nov);11: 987-992.
xxxvii) Pirie FJ, Motala AA, Amod A, Chetty R, Thomson SR, Lalloo S, Omar MAK.
Cushings Syndrome caused by ectopic ACTH secretion from pulmonary tumourlets. S Afr Med J. 2001(Nov); 11: 952-954.
xxxviii) Madiba TE, Rughubar KN, Haffejee AA, Motala AA.
Asymptomatic hyperparathyroidism caused by a giant parathyroid adenoma.
S Afr J Surg. 2002; 40(1):19-21.
xxxix) N Unwin, J. Shaw, P. Zimmet, G. Alberti. International Diabetes Federation IGT/IFG Consensus Statement. Report of an Expert Consensus Workshop (AlbertiKGMM…..Motala A.A…..Zimmet P). 1-4 August 2001, Stoke Poges, UK. Diabetic Med 2002; 19:708-723
xl) Motala AA.
Diabetes Trends in Africa
Diabetes Metab Res Rev (DMMR) 2002, 18 Suppl 3:S14-20
xli) Motala AA.
The Heart of the Matter: Cardiovascular Disease. Women and Diabetes.
Diabetes Voice (Bulletin of the International Diabetes Federation) 2002; 47: 37-39
xlii) Motala AA, Pirie FJ, Gouws E, Amod A, Omar MAK.
High incidence of type2 diabetes mellitus in South African Indians: a 10-year follow-up study.
Diabetic Medicine 2003 Jan;20(1):23-30.
xliii) Motala AA, Omar MAK, Pirie FJ.
Diabetes in Africa. Epidemiology of type 1 and type 2 diabetes in Africa.
J Cardiovasc Risk. 2003 Apr;10(2) : 77- 83
xliv) Al-Harbi EM, Abbassi AJ, Tamim H, al-Jenaidi F, Kooheji M, Kamal M, al-Mahroos S, al-Nasir F, Motala AA, Almawi WY.
Specific HLA-DRB and -DQB alleles and haplotypes confer disease susceptibility or resistance in Bahraini type 1 diabetes patients.
Clin Diagn Lab Immunol. 2004 Mar;11(2):292-6.
xlv) Almawi WY, Busson M, Tamim H, Al-Harbi EM, Finan RR, Wakim-Ghorayeb SF, Motala AA.
HLA class II profile and distribution of HLA-DRB1 and HLA-DQB1 alleles and haplotypes among Lebanese and BahrainiArabs. Clin Diagn Lab Immunol. 2004 Jul;11(4):770-4.
xlvi) Hung CC, Pirie F, Luan J, Lank E, Motala A, Yeo GS, Keogh JM, Wareham NJ, O’Rahilly S, Farooqi IS. Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.
Diabetes. 2004 Sep;53(9):2461-6.
xlvii) Almawi WY, Abou-Jaoude MM, Tamim H, Al-Harbi EM, Finan RR, Wakim-Ghorayeb SF, Motala AA.
Distribution of HLA class II (DRB1/DQB1) alleles and haplotypes among Bahraini and Lebanese Arabs.
Transplant Proc. 2004 Jul-Aug;36(6):1844-6.
xlviii) Motala AA, Busson M, Al-Harbi EM, Khuzam MA, Al-Omari EM, Arekat MR, Almawi WY.
Susceptible and protective human leukocyte antigen class II alleles and
haplotypes in bahraini type 2 (non-insulin-dependent) diabetes mellitus
patients.
Clin Diagn Lab Immunol. 2005 Jan;12(1):213-7.
xlix) Al-Jenaidi FA, Wakim-Ghorayeb SF, Al-Abbasi A, Arekat MR, Irani-Hakime N,Najm P, Al-Ola K, Motala AA, Almawi WY.
Contribution of selective HLA-DRB1/DQB1 alleles and haplotypes to the genetic susceptibility of type 1 diabetes among Lebanese and Bahraini Arabs. J Clin Endocrinol Metab. 2005; 90 : 5104-9.
l) Pirie FJ, Pegoraro R, Motala AA, Rauff S, Rom L, Govender T, Esterhuizen TM. Toll-like receptor 3 gene polymorphisms in South African Blacks with type 1 diabetes.
Tissue Antigens. 2005; 66(2):125-30.
li) Motala AA, Pirie F.J, Rauff S, Bacus HB.
Cost-effective management of diabetes mellitus.
Eth Dis. 2006 Spring; 16 (2 Suppl 2): 52-79-84
lii) Motala AA, Esterhuizen T, Gouws E, Pirie FJ, Omar MAK.
Diabetes mellitus and other disorders of glycaemia in a rural South African community: prevalence and associated risk factors.
DCare 2008 Sep;31(9):1783-8.
liii) Motala AA, Mbanya JC, Ramaiya KL.
Metabolic syndrome in sub-Saharan Africa.
Ethn Dis. 2009; 19(2 Suppl 2):S2-8-10.
liv) Mbanya JC, Motala AA, Sobngwi E, Assah FK, Enoru ST.
Diabetes in sub-Saharan Africa.
Lancet. 2010 Jun 26; 375(9733):2254-66.
lv) Pirie FJ, Motala AA, Pegararo RJ, Paruk IM, Govender I, Rom L. Variants in PPARG, KCNJ11, TCF7L2, and HHEX genes in South African subjects of Zulu descent with type 2 diabetes.
African Journal of Diabetes Medicine 2010;1: 17-21.
lvi) Motala AA, Esterhuizen T, Pirie FJ, Omar MAK. The Prevalence of Metabolic Syndrome and Determination of the Optimal Waist Circumference Cutoff Points in a Rural South African Community.
Diabetes Care. 2011 Apr; 34(4):1032-7.
lvii) Paruk IM, Pirie FJ, Motala AA, Kolawole BA.
High prevalence of abnormal liver enzymes in South African patients with type 2 diabetes mellitus attending a diabetes clinic. JEMDSA 2011; 16 (1): 43 – 47.
lviii) Beran D, Capewell S, de Courten M, Gale E, Gill G, Husseini A, Keen H, Motala A, O’Flaherty M, Ramachandran A, Swinburn B, Tesfaye S, Unwin N, Wild S, Yudkin JS.
The International Diabetes Federation: losing its credibility by partnering with Nestlé?
Lancet. 2012 Sep 1;380 (9844):805. doi: 10.1016/S0140-6736(12)61449-4.
lix) Paruk IM, Esterhuizen TM, Maharaj S, Pirie FJ, Motala AA.
Characteristics, management and outcome of primary hyperparathyroidism in South Africa: a single-centre experience.
Postgrad Med J. 2013 Nov;89(1057):626-31. doi: 10.1136/postgradmedj-2012-131707.
lx) Gaziano TA, Pandya A, Steyn K, Levitt N, Mollentze W, Joubert G, Walsh CM, Motala AA, Kruger A, Schutte AE, Naidoo DP, Prakaschandra DR and Laubscher R. Comparative Assessment of Absolute Cardiovascular Disease Risk Characterization from Non-laboratory-based Risk Assessment in South African Populations. BMC Med. 2013 Jul 24;11:170. doi: 10.1186/1741-7015-11-170.
lxi) Dillon DG, Gurdasani D, Riha J, Ekoru K, Asiki G, Mayanja BN, Levitt NS,
Crowther NJ, Nyirenda M, Njelekela M, Ramaiya K, Nyan O, Adewole OO, Anastos K, Azzoni L, Boom WH, Compostella C, Dave JA, Dawood H, Erikstrup C, Fourie CM, Friis H, Kruger A, Idoko JA, Longenecker CT, Mbondi S, Mukaya JE, Mutimura E, Ndhlovu CE, Praygod G, Pefura Yone EW, Pujades-Rodriguez M, Range N, Sani MU, Schutte AE, Sliwa K, Tien PC, Vorster EH, Walsh C, Zinyama R, Mashili F, Sobngwi E, Adebamowo C, Kamali A, Seeley J, Young EH, Smeeth L, Motala AA, Kaleebu P, Sandhu MS; African Partnership for Chronic Disease Research (APCDR).
Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis. Int J Epidemiol. 2013 Dec;42(6):1754-71. doi:10.1093/ije/dyt198.
lxii) Beagley J, Guariguata L, Weil C, Motala AA.
Global estimates of undiagnosed diabetes in adults for 2013 for the IDF Diabetes Atlas. Diabetes Res Clin Pract. 2014 Feb;103(2):150-60. doi: 10.1016/j.diabres.2013.11.001.
lxiii) Peer N, Kengne AP, Motala AA, Mbanya JC.
Diabetes in the Africa region: 2013 update for the IDF diabetes Atlas. Diabetes Res Clin Pract. 2014 Feb;103(2):197-205. doi: 10.1016/j.diabres.2013.11.006.
lxiv) Matovu E, Bucheton B, Chisi J, Enyaru J, Hertz-Fowler C, Koffi M, Macleod A, Mumba D, Sidibe I, Simo G, Simuunza M, Mayosi B, Ramesar R, Mulder N, Ogendo S, Mocumbi AO, Hugo-Hamman C, Ogah O, El Sayed A, Mondo C, Musuku J, Engel M, De Vries J, Lesosky M, Shaboodien G, Cordell H, Paré G, Keavney B, Motala A, Sobngwi E, Mbanya JC, Hennig B, Balde N, Nyirenda M, Oli J, Adebamowo C, Levitt N, Mayige M, Kapiga S, Kaleebu P, Sandhu M, Smeeth L, McCarthy M, Rotimi C. Research capacity. Enabling the genomic revolution in Africa. Science. 2014 Jun 20;344(6190):1346-8. doi: 10.1126/science.1251546.
lxv) Pirie FJ, Maharaj S, Esterhuizen T, Paruk IM, Motala AA. Retinopathy in subjects with type 2 diabetes at a tertiary diabetes clinic in Durban, South Africa: Clinical, biochemical and genetic factors. Journal of Clinical & Translational Endocrinology 1 (2014), e9-e12.doi: 10.1016/j.jcte 2013.12.002.
lxvi) Saloojee S, Burns JK, Motala AA. Very low rates of screening for metabolic
syndrome among patients with severe mental illness in Durban, South Africa. BMC Psychiatry. 2014 Aug 12;14(1):228. [Epub ahead of print].
lxvii) Dillon DG, Pirie F, Pomilla C, Sandhu MS, Motala AA, Young EH; African
Partnership for Chronic Disease Research (APCDR).
Open-source electronic data capture system offered increased accuracy and cost-effectiveness compared with paper methods in Africa.
J Clin Epidemiol. 2014 Aug 15. pii:S0895-4356(14)00238-8.
doi: 10.1016/j.jclinepi.2014.06.012.
lxviii) Gurdasani D, Carstensen T, Tekola-Ayele F, Pagani L, Tachmazidou I,
Hatzikotoulas K, Karthikeyan S, Iles L, Pollard MO, Choudhury A, Ritchie GR, Xue Y, Asimit J, Nsubuga RN, Young EH, Pomilla C, Kivinen K, Rockett K, Kamali A, Doumatey AP, Asiki G, Seeley J, Sisay-Joof F, Jallow M, Tollman S, Mekonnen E, Ekong R, Oljira T, Bradman N, Bojang K, Ramsay M, Adeyemo A, Bekele E, Motala A, Norris SA, Pirie F, Kaleebu P, Kwiatkowski D, Tyler-Smith C, Rotimi C, Zeggini E,Sandhu MS.
The African Genome Variation Project shapes medical genetics in Africa. Nature. 2015 Jan 15;517(7534):327-32. doi: 10.1038/nature13997
lxix) Shmendi A, Pirie F, Naidoo DP, Tlou B, Pilloy W, Motala AA.
Myocardial perfusion imaging for evaluation of suspected ischemia and its relationship with glycemic control in South African subjects with diabetes mellitus. Diabetes MetabSyndr Obes. 2014 Nov 14;7:545-52.
doi: 10.2147/DMSO.S72335. eCollection 2014.
lxx) Motala AA.
Diabetes in the Middle East: from Bedouins and pearl divers to the
scourge of diabetes.
J Diabetes. 2015 Sep;7(5):610-2. doi: 10.1111/1753-0407.12300. Epub 2015 May 27.
lxxi) Hird TR, Young EH, Pirie FJ, Riha J, Esterhuizen TM, O’Leary B, McCarthy MI, Sandhu, Motala AA.
Study profile: the Durban Diabetes Study (DDS): a platform for chronic disease research.
Global Health, Epidemiology and Genomics 2016; 1. January 2016, e5. DOI: http://dx.doi.org/10.1017/gheg.2015.3
lxxii) Ekoru K, Young EH, Adebamowo C, Balde N, Hennig BJ, Kaleebu P, Kapiga S, Levitt NS, Mayige M, Mbanya JC, McCarthy MI, Nyan O, Nyirenda M, Oli J, Ramaiya K, Smeeth L, Sobngwi E, Rotimi CN, Sandhu MS and Motala AA.
H3Africa Multi-Centre Study of the Prevalence and Environmental and Genetic Determinants of Type 2 Diabetes in Sub-Saharan Africa.
Global Health, Epidemiology and Genomics / Volume 1/ January 2016, e5. DOI: http://dx.doi.org/10.1017/gheg.2015.6
lxxiii) Prakaschandra DR, Esterhuizen TM, Motala AA, Gathiram P, Naidoo DP.
High prevalence of cardiovascular risk factors in Durban South African Indians: The Phoenix Lifestyle Project.
S Afr Med J. 2016 Feb 4;106(3):284-9. doi: 10.7196/SAMJ.2016.v106i3.9837.
lxxiv) Saloojee S, Burns JK, Motala AA.
Metabolic Syndrome in South African Patients with Severe Mental Illness: Prevalence and Associated Risk Factors.
PLoS One. 2016 Feb 16;11(2):e0149209. doi: 10.1371/journal.pone.0149209.
lxxv) Peprah E, Wiley K, Troyer J, Adebamowo SN, Adu D, Mayosi BM, Ramsay M, Motala AA, Adebamowo C, Ovbiagele B, Owolabi M; H3Africa Cardiovascular Diseases Working Group and as members of the H3Africa Consortium..
Building a Platform to Enable NCD Research to Address Population Health in Africa: CVD Working Group Discussion at the Sixth H3Africa Consortium Meeting in Zambia.
Glob Heart. 2016 Mar;11(1):165-70. doi: 10.1016/j.gheart.2015.11.002. No abstract available.
lxxvi) Hird TR, Pirie FJ, Esterhuizen TM, O’Leary B, McCarthy MI, Young EH, Sandhu MS, Motala AA.
Burden of Diabetes and First Evidence for the Utility of HbA1c for Diagnosis and Detection of Diabetes in Urban Black South Africans: The Durban Diabetes Study.
PLoS One. 2016 Aug 25;11(8):e0161966. doi: 10.1371/journal.pone.0161966.
lxxvii) Paruk IM, Ganie Y, Maharaj S, Pirie FJ, Naidoo VG, Nkwanyana NM, Dinnematin HL, Ramdial PK, Motala AA.
High prevalence of antithyroid peroxidase and antiparietal cell antibodies among patients with type 1 diabetes mellitus attending a tertiary diabetes centre in South Africa.
Postgrad Med J. 2016 Oct 14. pii: postgradmedj-2016-134420. doi: 10.1136/postgradmedj-2016-134420. [Epub ahead of print]
lxxviii) A. L. Barr, E. H. Young, L. Smeeth, R. Newton, J. Seeley, K. Ripullone, T. R. Hird, J. R. M. Thornton, M. J. Nyirenda, S. Kapiga, C. A. Adebamowo, A. G. Amoah, N. Wareham, C. N. Rotimi, N. S. Levitt, K. Ramaiya, B. J. Hennig, J. C. Mbanya, S. Tollman, A. A. Motala, P. Kaleebu, M. S. Sandhu.
The need for an integrated approach for chronic disease research and care in Africa.
Global Health, Epidemiology and Genomics / Volume 1 / 2016
DOI: https://doi.org/10.1017/gheg.2016.16. Published online: 29 November 2016, e19
lxxix) Elmezughi KK, Pirie FJ, Motala AA.
Characteristics and outcome of surgically treated pituitary tumours in South Africa: a single-centre experience.
Clin Endocrinol (Oxf). 2017 Apr;86(4):534-540. doi: 10.1111/cen.13279.
lxxx) Gill G, Yudkin JS, Tesfaye S, de Courten M, Gale E, Motala A, Ramaiya K, Unwin N, Wild S.
Essential medicines and access to insulin.
Lancet Diabetes Endocrinol. 2017 May;5(5):324-325. doi: 10.1016/S2213-8587(17)30090-6. Epub 2017 Mar 18.
lxxxi) Garst J, L’Heveder R, Siminerio LM, Motala AA, Gabbay RA, Chaney D, Cavan D.
Sustaining diabetes prevention and care interventions: A multiple case study of translational research projects.
Diabetes Res Clin Pract. 2017 May 19;130:67-76. doi: 10.1016/j.diabres.2017.04.025. [Epub ahead of print]
lxxxii) Saloojee S, Burns JK, Motala AA.
High risk of metabolic syndrome among black South African women with severe mental illness.
S Afr J Psychiat. 2017;23(0), a1089. https://doi.org/10.4102/ sajpsychiatry.v23i0.1089
lxxxiii) Gill G, Yudkin JS, Tesfaye S, de Courten M, Gale E, Motala A, Ramaiya K, Unwin N, Wild S. Essential medicines and access to insulin.
Lancet Diabetes Endocrinol. 2017 May;5(5):324-325. doi: 10.1016/S2213-8587(17)30090-6. Epub 2017 Mar 18.
lxxxiv) Ekoru K, Murphy GAV, Young EH, Delisle H, Jerome CS, Assah F, Longo-Mbenza B, Nzambi JPD, On’Kin JBK, Buntix F, Muyer MC, Christensen DL, Wesseh CS, Sabir A, Okafor C, Gezawa ID, Puepet F, Enang O, Raimi T, Ohwovoriole E, Oladapo OO, Bovet P, Mollentze W, Unwin N, Gray WK, Walker R, Agoudavi K, Siziya S, Chifamba J, Njelekela M, Fourie CM, Kruger S, Schutte AE, Walsh C, Gareta D, Kamali A, Seeley J, Norris SA, Crowther NJ, Pillay D, Kaleebu P, Motala AA, Sandhu MS.
Deriving an optimal threshold of waist circumference for detecting cardiometabolic risk in sub-Saharan Africa.
Int J Obes (Lond). 2017 Oct 3. doi: 10.1038/ijo.2017.240. [Epub ahead of print]
lxxxv) Motala AA. Chapter 1: Epidemiology of type 2 diabetes. The Society for Endocrinology, Metabolism and Diabetes of South Africa Type 2 Diabetes Guidelines Expert Committee. The 2017 SEMDSA Guideline for the Management of Type 2 Diabetes Guideline Committee.
JEMDSA 2017; 21(1) (Supplement 1): S8-S10.
lxxxvi) Motala AA. Chapter 2: Definition and classification of diabetes mellitus. The Society for Endocrinology, Metabolism and Diabetes of South Africa Type 2 Diabetes Guidelines Expert Committee. The 2017 SEMDSA Guideline for the Management of Type 2 Diabetes Guideline Committee.
JEMDSA 2017; 21(1) (Supplement 1): S11-S14.
lxxxvii) Motala AA. Chapter 3: Screening and diagnosis of type 2 diabetes and intermediate hyperglycaemia. The Society for Endocrinology, Metabolism and Diabetes of South Africa Type 2 Diabetes Guidelines Expert Committee. The 2017 SEMDSA Guideline for the Management of Type 2 Diabetes Guideline Committee.
JEMDSA 2017; 21(1) (Supplement 1): S15-S19.
lxxxviii) Saloojee S, Burns JK, Motala AA.
Metabolic syndrome in antipsychotic naive African patients with severe mental illness in usual care.
Early Interv Psychiatry. 2018; 12:1137-1143. doi: 10.1111/eip.12428.
lxxxix) Ekoru K, Young EH, Dillon DG, Gurdasani D, Stehouwer N, Faurholt-Jepsen D, Levitt NS, Crowther NJ, Nyirenda M, Njelekela MA, Ramaiya K, Nyan O, Adewole OO, Anastos K, Compostella C, Dave JA, Fourie CM, Friis H, Kruger IM, Longenecker CT, Maher DP, Mutimura E, Ndhlovu CE, Praygod G, Pefura Yone EW, Pujades-Rodriguez M, Range N, Sani MU, Sanusi M, Schutte AE, Sliwa K, Tien PC, Vorster EH, Walsh C, Gareta D, Mashili F, Sobngwi E, Adebamowo C, Kamali A, Seeley J, Smeeth L, Pillay D, Motala AA, Kaleebu P, Sandhu MS. HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.
Glob Health Epidemiol Genom. 2018;3. pii: e7. doi: 10.1017/gheg.2018.7. Epub 2018 May 8.
xc) Govender P, Elmezughi K, Esterhuizen T, Paruk I, Fraser JP, Motala AA. Characteristics of subjects with diabetes mellitus diagnosed before 35 years of age presenting to a tertiary diabetes clinic in Durban, South Africa, from 2003 to 2016.
JEMDSA 2018; 1(1): 1-6.
xci) Abdurraouf Esseid Zorgani, Fraser J Pirie, Ayesha A Motala.
Characteristics and outcome of patients with pheochromocytoma at a tertiary endocrinology clinic in Durban, South Africa over 14 years.
JEMDSA 2018: Volume 23, issue 2; pages 52-58. DOI:10.1080/16089677.2018.1446592.
xcii) Abdurraouf Masaud Elbueishi, Fraser J Pirie and Ayesha A Motala.
Characteristics and outcome of surgically treated acromegaly patients
attending an endocrinology clinic at a tertiary referral centre in Durban, South Africa over a period of 10 years.
JEMDSA 2018; 1(1):1–6.
xciii) Ekoru K, Murphy GAV, Young EH, Delisle H, Jerome CS, Assah F, Longo-Mbenza B, Nzambi JPD, On’Kin JBK, Buntix F, Muyer MC, Christensen DL, Wesseh CS, Sabir A, Okafor C, Gezawa ID, Puepet F, Enang O, Raimi T, Ohwovoriole E, Oladapo OO, Bovet P, Mollentze W, Unwin N, Gray WK, Walker R, Agoudavi K, Siziya S, Chifamba J, Njelekela M, Fourie CM, Kruger S, Schutte AE, Walsh C, Gareta D, Kamali A, Seeley J, Norris SA, Crowther NJ, Pillay D, Kaleebu P, Motala AA, Sandhu MS.
Deriving an optimal threshold of waist circumference for detecting cardiometabolic risk in sub-Saharan Africa.
Int J Obes 2018; 42:487-494. doi: 10.1038/ijo.2017.240
xciv) Tabesh M, Magliano DJ, Tanamas SK, Surmont F, Bahendeka S, Chiang CE, Elgart JF, Gagliardino JJ, Kalra S, Krishnamoorthy S, Luk A, Maegawa H, Motala AA, Pirie F, Ramachandran A, Tayeb K, Vikulova O, Wong J, Shaw JE.
Cardiovascular disease management in people with diabetes outside North America and Western Europe in 2006 and 2015.
Diabet Med. 2018 Nov 6. doi: 10.1111/dme.13858. [Epub ahead of print]
xcv) Owolabi MO, Akpa OM, Made F, Adebamowo SN, Ojo A, Adu D, Motala AA, Mayosi BM, Ovbiagele B, Adebamowo C, Tayo B, Rotimi C, Akinyemi R, Gebregziabher M, Sarfo F, Wahab KW, Parekh RS, Engel ME, Chisala C, Peprah E, Mensah G, Wiley K, Troyer J, Ramsay M.
Data resource profile: Cardiovascular H3Africa Innovation Resource (CHAIR). Int J Epidemiol. 2018 Dec 6. doi: 10.1093/ije/dyy261. [Epub ahead of print]
xcvi) Imran M Paruk, Fraser J Pirie and Ayesha A Motala.
Rickets mimicker: a report of two cases of primary hyperparathyroidism in
Adolescence
Journal of Endocrinology, Metabolism and Diabetes of South Africa 2019; 24(1):23–27. doi.org/10.1080/16089677.2018.1546365
xcvii) Paruk IM, Naidoo VG, Pirie FJ, Maharaj S, Nkwanyana NM, Dinnematin HL, Ganie Y, Ramdial PK, Motala AA.
Prevalence and characteristics of celiac disease in South African patients with type 1 diabetes mellitus: Results from the Durban Diabetes and Celiac Disease Study.
J Gastroenterol Hepatol. 2019 Jan 1. doi: 10.1111/jgh.14596. [Epub ahead of print]
xcviii) Paruk IM, Naidoo VG, Pirie FJ, Maharaj S, Nkwanyana NM, Dinnematin HL, Ganie Y, Ramdial PK, Motala AA.
Prevalence and characteristics of celiac disease in South African patients with type 1 diabetes mellitus: Results from the Durban Diabetes and Celiac Disease Study.
J Gastroenterol Hepatol. 2019 Apr;34(4):673-678. doi: 10.1111/jgh.14596. Epub 2019 Jan 31.
xcix) Tabesh M, Magliano DJ, Tanamas SK, Surmont F, Bahendeka S, Chiang CE, Elgart JF, Gagliardino JJ, Kalra S, Krishnamoorthy S, Luk A, Maegawa H, Motala AA, Pirie F, Ramachandran A, Tayeb K, Vikulova O, Wong J, Shaw JE.
Diabetes management and treatment approaches outside of North America and West Europe in 2006 and 2015.
Acta Diabetol. 2019 Apr 8. doi: 10.1007/s00592-018-01284-4. [Epub ahead of print]
c) Paruk IM, Pirie FJ, Motala AA.
Non-alcoholic fatty liver disease in Africa: a hidden danger.
Glob Health Epidemiol Genom. 2019 Apr 12; 4:e3. doi: 10.1017/gheg.2019.2. eCollection 2019.
i) Motala AA.
Insulin use in non-insulin dependent diabetes mellitus.
Spec Med 1994; xvi : 50-60.
ii) Motala AA.
Management of Hypertension in diabetes mellitus.
Hypertension in Progress 1996;
iii) Motala AA.
Microalbuminuria in diabetes mellitus.
Specialist Medicine 1998; xx : 54-65.
PUBLICATIONS – BOOKS/CHAPTERS IN BOOKS/THESIS
i) Motala AA.
Impaired Glucose Tolerance (IGT) : A study in South African Indians in Durban.
M.D. Thesis – University of Natal 1990.
ii) Omar MAK, Motala AA, Seedat MA.
Microvascular complications in South African Indians with non-insulin dependent diabetes of the young in Van Schilfgaarde R (ed): Complications of diabetes.
Grune and Stratten Inc 1987.
iii) Omar MAK, Motala AA.
Asian immigrant diabetes 2 – South Africa. In Gill R, Mbanya J-C, Alberti G eds. Diabetes in Africa, FSG Communications Ltd, Cambridge; 1997.
iv) Motala AA, Omar MAK, Pirie FJ.
The epidemiology of diabetes; An international perspective: Africa. In Ekoe JM, Williams Rhys, Zimmet P (ed) :The Epidemiology of diabetes mellitus: An International Perspective. John Wiley, 2001:225-232.
v) Motala AA, Omar MAK, Pirie FJ.
Epidemiology of Diabetes in Africa. In Ekoe JM, Williams Rhys, Zimmet P (ed):The Epidemiology of diabetes mellitus: An International Perspective. John Wiley, 2008: Chapter 11.
vi) Motala AA and Pirie FJ.
Diabetes in the Tropics. Cook and Zumla (ed): Manson’s Tropical Diseases 22ed. 2008
vii) Motala AA and Pirie FJ.
Diabetes in the Tropics. Cook and Zumla (ed): Manson’s Tropical Diseases 23rd ed. 2014.
viii) Omar MAK and Motala AA.
Prevention of diabetes in Africa. Ogunmekan DA, Seedat YK, Osibogun A, Onajole (ed). University of Lagos Press and Bookshop Ltd. Public Health in Africa. 2018.
Researcher: Prof Imran M Paruk
i) Pirie FJ, Motala AA, Pegararo RJ, Paruk IM, Govender I, Rom L. Variants in PPARG, KCNJ11, TCF7L2, and HHEX genes in South African subjects of Zulu descent with type 2 diabetes.
African Journal of Diabetes Medicine 2010;1: 17-21.
ii) Paruk IM, Pirie FJ, Motala AA, Kolawole BA.
High prevalence of abnormal liver enzymes in South African patients with type 2 diabetes mellitus attending a diabetes clinic. JEMDSA 2011; 16 (1): 43 – 47.
iii) Paruk IM, Esterhuizen TM, Maharaj S, Pirie FJ, Motala AA.
Characteristics, management and outcome of primary hyperparathyroidism in South Africa: a single-centre experience.
Postgrad Med J. 2013 Nov;89(1057):626-31. doi: 10.1136/postgradmedj-2012-131707.
iv) Pirie FJ, Maharaj S, Esterhuizen T, Paruk IM, Motala AA. Retinopathy in subjects with type 2 diabetes at a tertiary diabetes clinic in Durban, South Africa: Clinical, biochemical and genetic factors. Journal of Clinical & Translational Endocrinology 1 (2014), e9-e12.doi: 10.1016/j.jcte 2013.12.002.
v) Paruk IM, Ganie Y, Maharaj S, Pirie FJ, Naidoo VG, Nkwanyana NM, Dinnematin HL, Ramdial PK, Motala AA.
High prevalence of antithyroid peroxidase and antiparietal cell antibodies among patients with type 1 diabetes mellitus attending a tertiary diabetes centre in South Africa.
Postgrad Med J. 2016 Oct 14. pii: postgradmedj-2016-134420. doi: 10.1136/postgradmedj-2016-134420. [Epub ahead of print]
vi) Govender P, Elmezughi K, Esterhuizen T, Paruk I, Fraser JP, Motala AA. Characteristics of subjects with diabetes mellitus diagnosed before 35 years of age presenting to a tertiary diabetes clinic in Durban, South Africa, from 2003 to 2016.
JEMDSA 2018; 1(1): 1-6.
vii) Imran M Paruk, Fraser J Pirie and Ayesha A Motala.
Rickets mimicker: a report of two cases of primary hyperparathyroidism in
Adolescence
Journal of Endocrinology, Metabolism and Diabetes of South Africa 2019; 24(1):23–27. doi.org/10.1080/16089677.2018.1546365
viii) Paruk IM, Naidoo VG, Pirie FJ, Maharaj S, Nkwanyana NM, Dinnematin HL, Ganie Y, Ramdial PK, Motala AA.
Prevalence and characteristics of celiac disease in South African patients with type 1 diabetes mellitus: Results from the Durban Diabetes and Celiac Disease Study.
J Gastroenterol Hepatol. 2019 Jan 1. doi: 10.1111/jgh.14596. [Epub ahead of print]
ix) Paruk IM, Naidoo VG, Pirie FJ, Maharaj S, Nkwanyana NM, Dinnematin HL, Ganie Y, Ramdial PK, Motala AA.
Prevalence and characteristics of celiac disease in South African patients with type 1 diabetes mellitus: Results from the Durban Diabetes and Celiac Disease Study.
J Gastroenterol Hepatol. 2019 Apr;34(4):673-678. doi: 10.1111/jgh.14596. Epub 2019 Jan 31.
x) Paruk IM, Pirie FJ, Motala AA.
Non-alcoholic fatty liver disease in Africa: a hidden danger.
Glob Health Epidemiol Genom. 2019 Apr 12; 4:e3. doi: 10.1017/gheg.2019.2. eCollection 2019.
Researcher: Dr Khaled Elmezughi.
Designation:
Summary: Aims:To describe the clinical, biochemical, radiological and histological features and to determine the outcome of all patients with pituitary tumours treated surgically at Inkosi Albert Luthuli Central Hospital in Durban over a 5 year period.
Research design: Retrospective chart review from 2008 to 2012. Clinical, biochemical and radiologic data were collected before and one year after surgery. Histopathology findings and perioperative complications were recorded.
Results: Seventy patients were included (age 44.8±14.9 years, 55.7% female). Headache (84.1%) and visual disturbance (78.3%) were the predominant presenting symptoms. Most tumours were macroadenomata (97.1%). Trans-sphenoidal surgery was employed in the majority (90%). A single procedure was required in 55.7% patients, two procedures in 30% and up to six in others. Medical therapy was used in 22 (31.4%) and radiotherapy in 13 (18.6%). Complete resection was achieved only in 9 patients (12.8%), residual tumour post-surgery was found in 48 (68.6%) and there was no change in tumour size in 13 patients (18.6%). On biopsy, the most common pathology was non-functional adenoma in 33 (47.1%); 29 (41.4%) were secretory tumours. Overall mortaility was 4.3%. The commonest surgical complication was cerebrospinal fluid (CSF) leak (10%; n=7). New post-surgical pituitary hypofunction occurred in 62 (88.6%). The outcome at one year was similar to that on dischage.
Conclusions: Patients presenting to IALCH had large tumours and complete resection was achieved in a minority. There was a low overall mortality but high rate of post-surgical pituitary hypofunction.
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